Product name: Benzocaine;Anesthesin;Parathesin;Auralgan Otic;Ethyl
Alias: Americaine; ETHYL P-AMINOBENZOATE
CAS register number:94-09-7
Appearance: White crystalline powder
Grade : Pharmaceutical Grade
Storage: Shading, confined preservation
Pain is caused by the stimulation of free nerve endings. When the
nerve endings are stimulated, sodium enters the neuron, causing
depolarization of the nerve and subsequent initiation of an action
potential. The action potential is propagated down the nerve toward
the central nervous system, which interprets this as pain.
Benzocaine acts to inhibit the voltage-dependent sodium channels
(VDSCs) on the nerve membrane, stopping the propagation of the
Benzocaine is used as a key ingredient in numerous
pharmaceuticals:Over the counter throat lozenges such as
Cepacol.Some glycerol-based ear medications for use in removing
excess wax as well as relieving ear conditions such as otitis media
and swimmers ear.Some previous diet products such as Ayds.Some
condoms designed to prevent premature ejaculation. Benzocaine
largely inhibits sensitivity on the penis, and can allow for an
erection to be maintained longer (in a continuous act) by delaying
ejaculation. Conversely, an erection will also fade faster if
stimulus is interrupted.Benzocaine mucoadhesive patches have been
used in reducing orthodontic pain.
Benzocaine is a kind of fat-soluble surface anesthetic. Compared
with several other topical anesthetics such as lidocaine,
tetracaine, its intensity is small, so it won't make people feel
discomfort because of the anesthesia effect on the mucosa. It is a
very strong fat-soluble drugs with easy combination with mucosa or
skin and not easy penetration into body to produce toxicity.
Benzocaine can be used as the raw materials of Otho imitation,
Orthocaine and Procaine; at the same time, it is used as a topical
anesthetics in medicine with analgesic, antipruritic effect, mainly
used for wounds, ulcers, mucosal surface anesthesia plane and
hemorrhoids pain and itching. Its ointment can also be used as the
lubrication of nasopharyngeal catheter, sudden pain within the
endoscope mirror etc.. To relief the pain and discomfort of skin
itching such as minor burns, sunburn, trauma and insect bites. Ear
preparation is used to reduce acute congestive, concentrated otitis
externa, swimming otitis pain and itching and external ear. It is
also effective for toothache, sore throat, oral ulcer, hemorrhoids,
anal fissure, pruritus vulvae. Benzocaine can be usded as male
genital desensitizer to make ejaculation slow or anesthesia
lubricant of endoscopic tube and catheter.
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The quality control process:
Thorough market research, understand the price of raw materials and
performance.To the procurement source to understand fully, and
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