58-20-8 Cypionate Testosterone Anabolic Steroid Andronate
We can supply its raw material powder with the best quality and
Testosterone cypionate (brand names Depo-Testosterone, many
others), or testosterone cipionate, also known as testosterone
cyclopentylpropionate or testosterone cyclopentanepropionate, is an
androgen and anabolic steroid and a testosterone ester. Along with
testosterone enanthate, testosterone propionate, and testosterone
undecanoate, it is one of the most widely used testosterone esters.
Testosterone Cypionate Description
Testosterone Cypionate Injection, for intramuscular injection,
contains Testosterone Cypionate which is the oil-soluble 17 (beta)-
cyclopentylpropionate ester of the androgenic hormone testosterone.
Testosterone Cypionate is a white or creamy white crystalline
powder, odorless or nearly so and stable in air. It is insoluble in
water, freely soluble in alcohol, chloroform, dioxane, ether, and
soluble in vegetable oils.
The chemical name for Testosterone Cypionate is androst-4-en-3-one,
17-(3-cyclopentyl-1-oxopropoxy)-, (17ß)-. Its molecular formula is
C27H40O3, and the molecular weight 412.61.
Testosterone Cypionate Injection is available in two strengths, 100
mg/mL and 200 mg/mL Testosterone Cypionate.
|Each mL of the 100 mg/mL solution contains:|
|Testosterone Cypionate||100 mg|
|Benzyl benzoate||0.1 mL|
|Cottonseed oil||736 mg|
|Benzyl alcohol (as preservative)||9.45 mg|
|Each mL of the 200 mg/mL solution contains:|
|Testosterone Cypionate||200 mg|
|Benzyl benzoate||0.2 mL|
|Cottonseed oil||560 mg|
|Benzyl alcohol (as preservative)||9.45 mg|
Testosterone is a hormone produced by all human beings and is the
primary male sex hormone. Through our discussion, well take a look
atTestosterone Cypionate, and examine the pros and cons of its use
to improve performance in athletics and bodybuilding. Before we
dive in, lets clear up a common misconception. Testosterone
Cypionate is no more or less powerful or effective than its
counterpart Testosterone Enanthate. The two compounds are virtually
identical in every way.
Testosterone Cypionate Traits
Testosterone Cypionate is a synthetic version of the naturally
produced testosterone hormone. This hormone is responsible for many
different physical and mental characteristics in males. It promotes
sex drive, fat loss, helps with gaining and maintaining lean muscle
mass, increases bone density, and may even protect against heart
disease. Whether it is naturally produced or through the use of
Testosterone Cypionate, these traits do not change. All other
steroids are actually the testosterone molecule that has been
altered to change the properties of the hormone.
Testosterone Cypionate carries a rating of 100 when measuring its
anabolic/androgenic structure and this rating is used to measure
all other steroids. This would make testosterone the "father" of
all anabolic steroids used by athletes today.
It should be noted; all testosterone compounds, including
Testosterone Cypionate carry this anabolic/androgenic score of 100,
as they are all merely testosterone.
Testosterone Cypionate is a highly anabolic and androgenic hormone
making it a great steroid to use if one is in pursuit of more size
and strength. Testosterone Cypionate promotes nitrogen retention in
the muscle and the more nitrogen the muscles hold the more protein
the muscles store.
Testosterone Cypionate can also increase the levels of another
anabolic hormone, IGF-1 in muscle tissue providing even more
anabolic activity. Testosterone Cypionate also has the amazing
ability to increase the activity of satellite cells. These cells
play an active role in repairing damaged muscle. Testosterone also
binds to the androgen receptor to promote androgen receptor
dependent mechanisms for muscle gain and fat loss.
Testosterone Cypionate induces changes in shape, size and can also
change the appearance and the number of muscle fibers. Androgens
like testosterone can protect your hard earned muscle from the
catabolic (muscle wasting) glucocorticoid hormones, in-turn
inhibiting the related adverse reactions. In addition, Testosterone
Cypionate has the ability to increase red blood cell production and
a higher red blood cell count will improve endurance through
increased oxygenation in the blood. More red blood cells can also
improve recovery from strenuous physical activity.
Even so, Testosterones anabolic/androgenic effects are dose
dependent; the higher the dose the higher the muscle building
Many athletes display massive strength gains while using
Testosterone Cypionate as the hormone improves muscle contraction
by increasing the number of motor neutrons in muscle and improves
It also promotes glycogen synthesis providing more fuel for
intenseworkouts thereby increasing endurance and strength.
Testosterone Cypionate also has the ability to promote fat loss
through an enhancement of metabolic activity. Testosterone binds to
the androgen receptor fairly well resulting in fat breakdown, and
further prevents new fat cell formation. Another indirect action of
fat loss that testosterone produces is the nutrient portioning
effect it has on muscle and fat. Since the body is building muscle
at an accelerated rate more of the food you eat is shuttled to
muscle tissue instead of being stored as fat; nutrient efficiency
Testosterone Cypionate will also play a crucial role revolving
around creatine. Creatine is essential to adenosine triphosphate
(ATP), the source of energy for our muscles and when the muscles
are stimulated ATP is broken down into adenosine diphosphate (ADP)
and this is what releases energy. Unfortunately, the process is
often too slow during strenuous activity but through the use of
Testosterone Cypionate, this demand is met as ATP is replenished at
a much faster rate.
Effects of Testosterone Cypionate
With a well-planned Testosterone Cypionate cycle, nearly every
anabolic steroid benefit can be obtained. For the off-season
athlete, more lean muscle mass can be built with less body fat
gain. In-order to grow, you must consume enough calories and fat
gain will occur, but Testosterone Cypionate will ensure the brunt
of your weight gain is the weight you want.
While off-season bulking use is the most common, the effects of
Testosterone Cypionate can be tremendously beneficial during the
cutting phase too. During this period of use, we are able to
preserve far more lean muscle tissue that would otherwise be lost.
In-order to lose body fat, we must burn more calories than we
consume and this can and often does lead to muscle and strength
loss. Further, the longer and harder you diet the more muscle and
strength will be at risk, but due to the traits of Testosterone
Cypionate muscle tissue and strength are protected.
Regardless of the purpose of use, Testosterone Cypionate defines
performance enhancement by its ability to promote recovery and
endurance. With a performance level dose of Testosterone Cypionate
your body can recover faster and you wont tire out as quickly. This
will allow you toworkout longer and harder, and more progress can
be made. This is performance enhancement at its best.
Testosterone Cypionate Administration
Testosterone Cypionate is only available in an injectable form and
is regularly used to treat conditions such as low testosterone.
More than twenty million men in the U.S. alone suffer from some
form of low testosterone, and such a condition can severely
diminish ones quality of life. Symptoms such as loss of muscle mass
and strength, a decrease in libido and sexual performance, an
increase in body fat, and low energy levels are all common
characteristics of low testosterone.
Further, when ignored low testosterone can be a gateway to
Alzheimers, diabetes, osteoporosis and many other serious
conditions. Most men will find one injection every seven to ten
days at 100mg to 200mg per injection to completely eradicate such a
For performance enhancement, one injection per week is often
enough; however, in many cases two smaller yet equal sized
injections will prove to be far more efficient. The reason for
multiple injections is to keep blood levels peaked; further, it is
often needed to control side effects that may occur with
performance level dosing.
Like most anabolic steroids, the more you take the greater the
reward, but the more you take the greater the risk. By splitting
the injections up into smaller more frequent injections, you are
introducing smaller amounts of the hormone for your body to deal
with all at once. As for the actual performance doses, this can
range anywhere from 200mg per week all the way to 1,000mg per week
depending on needs and desires.
The typical dose for those who are using Cypionate to counteract
the lowering of testosterone due to the use of other steroids is
normally 200mg. If it is being used for direct performance
purposes, most will find 400mg to 600mg per week will be effective,
but it is important to note that higher doses will greatly increase
Regardless of the total dose, most steroid users will find this to
be an extremely well-tolerated anabolic steroid and one that can be
used for long periods of time. 12 weeks of total use is quite
commonplace, as is 16 weeks. There's nothing magical about these
numbers, but they are solid guidelines in-order for the individual
to plan out his desired goals.
Regardless of the total dosing or the cycles length, you will need
to design a post cycle therapy (PCT) plan once your Testosterone
Cypionate use comes to an end. For most men, if you are
discontinuing the use of anabolic steroids for more than ten weeks,
you will need PCT but if your off period is less then it can be
skipped. For full post cycle information and planning, please see
the Post Cycle Therapy page on Steroid.com.
It should be noted; when it comes to performance enhancement,
Testosterone Cypionate for women is not recommended. This is a
steroid that carries far too much androgenic activity; after all,
it is the primary male androgen. Women can suffer from low
testosterone and there can be therapeutic benefits from the use of
Testosterone Cypionate; however such treatment plans will be
tremendously low dosed and should be watched closely for
The Side Effects of Testosterone Cypionate
As an extremely well-tolerated hormone for most men, the side
effects of Testosterone Cypionate are in many ways easy to control.
When it comes to such adverse reactions, keep in mind they largely
fall into the realm of possible and are by no means guaranteed.
Even so, total dosing, genetic predispositions and your overall
state of health will play a role.
As for the side effects themselves, Testosterone Cypionate like all
testosterone compounds carries a high level of aromatase activity;
aromatization referring to the conversion of testosterone into
estrogen. As estrogen levels rise, this can lead to gynecomastia
(male breast enlargement) and excess water retention. This excess
water retention can even negatively affect blood pressure. In-order
to combat such effects, especially gynecomastia, many turn to
Selective Estrogen Receptor
odulators (SERMs) such as Tamoxifen Citrate (Nolvadex) and for more
serious protection Aromatase Inhibitors (AIs) such as Anastrozole
(Arimidex). Without question, AIs are the most effective; however,
they can also prove to be problematic when it comes to cholesterol
and caution is advised.
Beyond these effects, Testosterone Cypionate can promote
dihydrotestosterone (DHT) related side effects such as acne, hair
loss and prostate enlargement; however, it should go without saying
DHT steroids will be the prime culprits. In-order to provide
protection, a 5-alpha reductase inhibitor such as Finasteride can
be useful as it is an androgen suppressor and the androgen DHT is
causing the problem. It must be noted; hair loss is only possible
in men predisposed to male pattern baldness.
Availability of Testosterone Cypionate
If you live in the U.S. you will not find Testosterone Cypionate
for sale on the black market as commonly as you will many other
testosterone forms; especially when it comes to pharmaceutical
grade. The vast majority of Testosterone Cypionate is manufactured
in the U.S. by Upjohn and Watson, and very little ever finds its
way to black market suppliers. Of course, outside the U.S. things
begin to change as there are quite a few pharmaceutical companies
that make it. Further, numerous underground labs across the globe
manufacture the product.
Regardless of the brand you choose, most Testosterone Cypionate
comes dosed at 200mg/ml or 250mg/ml. There are a few exceptions;
however, most high dosed Testosterone Cypionate normally falls
under the category of buyer beware. Such products are commonly
under-dosed and are only provided by low-grade underground labs. Of
course, regardless of the dosing, you must be very careful when
making any anabolic steroid purchase. Contaminated products are not
uncommon, and when it comes to human grade Testosterone Cypionate
this is one of the most commonly counterfeited testosterones.
Buying Testosterone Cypionate Online - Warning
You can easily buy Testosterone Cypionate online; in-fact, this is
the easiest and most common way to make an anabolic steroid
purchase. Even so, anabolic steroids are classified as Schedule III
controlled substances in the U.S. and carry severe legal
ramifications if the law is broken. For this reason, if you desire
to stay within the safety of the law while meeting your anabolic
needs, please see the sponsors and advertisers here at steroid.com.
Here you will find high quality anabolics that are not only
effective but also legal without a prescription.
With many anabolic steroids to choose from, very few carry such a
high level of versatility and toleration as Testosterone Cypionate.
Perfect for beginners and long time steroid users in any cycle, it
is impossible to go wrong with this steroid.
If youre new to anabolic steroids and youve maxed out your natural
potential, this is the perfect steroid to see your progress
continue once again. If you are an advanced steroid user and have
used Cypionate in past cycles, it will continue to be just as
effective each and every time. This is not an anabolic steroid
reserved for a particular group of people, or one that is only
useful at one specific time but rather a solid foundational steroid
that is perfect for any cycle.
Testosterone Cypionate - Clinical Pharmacology
Endogenous androgens are responsible for normal growth and
development of the male sex organs and for maintenance of secondary
sex characteristics. These effects include growth and maturation of
the prostate, seminal vesicles, penis, and scrotum; development of
male hair distribution, such as beard, pubic, chest, and axillary
hair; laryngeal enlargement, vocal cord thickening, and alterations
in body musculature and fat distribution.
Drugs in this class also cause retention of nitrogen, sodium,
potassium, and phosphorous, and decreased urinary excretion of
calcium. Androgens have been reported to increase protein anabolism
and decrease protein catabolism. Nitrogen balance is improved only
when there is sufficient intake of calories and protein.
Androgens are responsible for the growth spurt of adolescence and
for eventual termination of linear growth, brought about by fusion
of the epiphyseal growth centers.
In children, exogenous androgens accelerate linear growth rates,
but may cause disproportionate advancement in bone maturation. Use
over long periods may result in fusion of the epiphyseal growth
centers and termination of the growth process.
Androgens have been reported to stimulate production of red blood
cells by enhancing production of erythropoietic stimulation factor.
During exogenous administration of androgens, endogenous
testosterone release is inhibited through feedback inhibition of
pituitary luteinizing hormone (LH). At large doses of exogenous
androgens, spermatogenesis may also be suppressed through feedback
inhibition of pituitary follicle stimulating hormone (FSH).
There is a lack of substantial evidence that androgens are
effective in fractures, surgery, convalescence, and functional
Testosterone esters are less polar than free testosterone.
Testosterone esters in oil injected intramuscularly are absorbed
slowly from the lipid phase; thus, Testosterone Cypionate can be
given at intervals of two to four weeks.
Testosterone in plasma is 98 percent bound to a specific
testosterone-estradiol binding globulin, and about 2 percent is
free. Generally, the amount of this sex-hormone binding globulin in
the plasma will determine the distribution of testosterone between
free and bound forms, and the free testosterone concentration will
determine its half-life.
About 90 percent of a dose of testosterone is excreted in the urine
as glucuronic and sulfuric acid conjugates of testosterone and its
metabolites; about 6 percent of a dose is excreted in the feces,
mostly in the unconjugated form. Inactivation of testosterone
occurs primarily in the liver. Testosterone is metabolized to
various 17-keto steroids through two different pathways.
The half-life of Testosterone Cypionate when injected
intramuscularly is approximately eight days.
In many tissues the activity of testosterone appears to depend on
reduction to dihydrotestosterone, which binds to cytosol receptor
proteins. The steroid-receptor complex is transported to the
nucleus where it initiates transcription events and cellular
changes related to androgen action.
Indications and Usage for Testosterone Cypionate
Testosterone Cypionate Injection is indicated for replacement
therapy in the male in conditions associated with symptoms of
deficiency or absence of endogenous testosterone.
1. Primary hypogonadism (congenital or acquired)-testicular failure
due to cryptorchidism, bilateral torsion, orchitis, vanishing
testis syndrome; or orchidectomy.
2. Hypogonadotropic hypogonadism (congenital or acquired)-
gonadotropin or LHRH deficiency, or pituitary-hypothalamic injury
from tumors, trauma, or radiation.
Safety and efficacy of Testosterone Cypionate Injection in men with
"age-related hypogonadism" (also referred to as "late-onset
hypogonadism") have not been established.
Known hypersensitivity to the drug
Males with carcinoma of the breast
Males with known or suspected carcinoma of the prostate gland
Women who are or who may become pregnant
Patients with serious cardiac, hepatic or renal disease
Hypercalcemia may occur in immobilized patients. If this occurs,
the drug should be discontinued.
Prolonged use of high doses of androgens (principally the 17-α
alkyl-androgens) has been associated with development of hepatic
adenomas, hepatocellular carcinoma, and peliosis hepatis —all
potentially life-threatening complications.
Geriatric patients treated with androgens may be at an increased
risk of developing prostatic hypertrophy and prostatic carcinoma
although conclusive evidence to support this concept is lacking.
There have been postmarketing reports of venous thromboembolic
events, including deep vein thrombosis (DVT) and pulmonary embolism
(PE), in patients using testosterone products, such as Testosterone
Cypionate. Evaluate patients who report symptoms of pain, edema,
warmth and erythema in the lower extremity for DVT and those who
present with acute shortness of breath for PE. If a venous
thromboembolic event is suspected, discontinue treatment with
Testosterone Cypionate and initiate appropriate workup and
Long term clinical safety trials have not been conducted to assess
the cardiovascular outcomes of testosterone replacement therapy in
men. To date, epidemiologic studies and randomized controlled
trials have been inconclusive for determining the risk of major
adverse cardiovascular events (MACE), such as non-fatal myocardial
infarction, non-fatal stroke, and cardiovascular death, with the
use of testosterone compared to non-use.
Some studies, but not all, have reported an increased risk of MACE
in association with use of testosterone replacement therapy in men.
Patients should be informed of this possible risk when deciding
whether to use or to continue to use Testosterone Cypionate
Abuse of Testosterone and Monitoring of Serum Testosterone
Testosterone has been subject to abuse, typically at doses higher
than recommended for the approved indication and in combination
with other anabolic androgenic steroids. Anabolic androgenic
steroid abuse can lead to serious cardiovascular and psychiatric
If testosterone abuse is suspected, check serum testosterone
concentrations to ensure they are within therapeutic range.
However, testosterone levels may be in the normal or subnormal
range in men abusing synthetic testosterone derivatives.
Counsel patients concerning the serious adverse reactions
associated with abuse of testosterone and anabolic androgenic
steroids. Conversely, consider the possibility of testosterone and
anabolic androgenic steroid abuse in suspected patients who present
with serious cardiovascular or psychiatric adverse events.
Edema, with or without congestive heart failure, may be a serious
complication in patients with pre-existing cardiac, renal or
Gynecomastia may develop and occasionally persists in patients
being treated for hypogonadism.
The preservative benzyl alcohol has been associated with serious
adverse events, including the "gasping syndrome", and death in
pediatric patients. Although normal therapeutic doses of this
product ordinarily deliver amounts of benzyl alcohol that are
substantially lower than those reported in association with the
"gasping syndrome", the minimum amount of benzyl alcohol at which
toxicity may occur is not known.
The risk of benzyl alcohol toxicity depends on the quantity
administered and the liver and kidneys' capacity to detoxify the
chemical. Premature and low-birth weight infants may be more likely
to develop toxicity.
Androgen therapy should be used cautiously in healthy males with
delayed puberty. The effect on bone maturation should be monitored
by assessing bone age of the wrist and hand every 6 months. In
children, androgen treatment may accelerate bone maturation without
producing compensatory gain in linear growth. This adverse effect
may result in compromised adult stature. The younger the child the
greater the risk of compromising final mature height.
This drug has not been shown to be safe and effective for the
enhancement of athletic performance. Because of the potential risk
of serious adverse health effects, this drug should not be used for
Patients with benign prostatic hypertrophy may develop acute
urethral obstruction. Priapism or excessive sexual stimulation may
develop. Oligospermia may occur after prolonged administration or
excessive dosage. If any of these effects appear, the androgen
should be stopped and if restarted, a lower dosage should be
Testosterone Cypionate should not be used interchangeably with
testosterone propionate because of differences in duration of
Testosterone Cypionate is not for intravenous use.
Information for patients
Patients should be instructed to report any of the following:
nausea, vomiting, changes in skin color, ankle swelling, too
frequent or persistent erections of the penis.
Hemoglobin and hematocrit levels (to detect polycythemia) should be
checked periodically in patients receiving long-term androgen
Serum cholesterol may increase during androgen therapy.
Androgens may increase sensitivity to oral anticoagulants. Dosage
of the anticoagulant may require reduction in order to maintain
satisfactory therapeutic hypoprothrombinemia.
Concurrent administration of oxyphenbutazone and androgens may
result in elevated serum levels of oxyphenbutazone.
In diabetic patients, the metabolic effects of androgens may
decrease blood glucose and, therefore, insulin requirements.
Drug/Laboratory test Interferences
Androgens may decrease levels of thyroxine-binding globulin,
resulting in decreased total T4 serum levels and increased resin
uptake of T3 and T4. Free thyroid hormone levels remain unchanged,
however, and there is no clinical evidence of thyroid dysfunction.
Testosterone has been tested by subcutaneous injection and
implantation in mice and rats. The implant induced cervical-uterine
tumors in mice, which metastasized in some cases. There is
suggestive evidence that injection of testosterone into some
strains of female mice increases their susceptibility to hepatoma.
Testosterone is also known to increase the number of tumors and
decrease the degree of differentiation of chemically induced
carcinomas of the liver in rats.
There are rare reports of hepatocellular carcinoma in patients
receiving long-term therapy with androgens in high doses.
Withdrawal of the drugs did not lead to regression of the tumors in
Geriatric patients treated with androgens may be at an increased
risk of developing prostatic hypertrophy and prostatic carcinoma
although conclusive evidence to support this concept is lacking.
Pregnancy Category X
Benzyl alcohol can cross the placenta. .
Testosterone Cypionate Injection is not recommended for use in
Safety and effectiveness in pediatric patients below the age of 12
years have not been established.
The following adverse reactions in the male have occurred with some
Endocrine and urogenital: Gynecomastia and excessive frequency and
duration of penile erections. Oligospermia may occur at high
Skin and appendages: Hirsutism, male pattern of baldness,
seborrhea, and acne.
Cardiovascular Disorders: myocardial infarction, stroke.
Fluid and electrolyte disturbances: Retention of sodium, chloride,
water, potassium, calcium, and inorganic phosphates.
Gastrointestinal: Nausea, cholestatic jaundice, alterations in
liver function tests, rarely hepatocellular neoplasms and peliosis
hepatis (see WARNINGS).
Hematologic: Suppression of clotting factors II, V, VII, and X,
bleeding in patients on concomitant anticoagulant therapy, and
Nervous system: Increased or decreased libido, headache, anxiety,
depression, and generalized paresthesia.
Allergic: Hypersensitivity, including skin manifestations and
Vascular disorders: Venous thromboembolism.
Miscellaneous: Inflammation and pain at the site of intramuscular
Drug Abuse and Dependence
Testosterone Cypionate Injection contains testosterone, a Schedule
III controlled substance in the Controlled Substances Act.
Drug abuse is intentional non-therapeutic use of a drug, even once,
for its rewarding psychological and physiological effects. Abuse
and misuse of testosterone are seen in male and female adults and
adolescents. Testosterone, often in combination with other anabolic
androgenic steroids (AAS), and not obtained by prescription through
a pharmacy, may be abused by athletes and bodybuilders. There have
been reports of misuse by men taking higher doses of legally
obtained testosterone than prescribed and continuing testosterone
despite adverse events or against medical advice.
Abuse-Related Adverse Reactions
Serious adverse reactions have been reported in individuals who
abuse anabolic androgenic steroids and include cardiac arrest,
myocardial infarction, hypertrophic cardiomyopathy, congestive
heart failure, cerebrovascular accident, hepatotoxicity, and
serious psychiatric manifestations, including major depression,
mania, paranoia, psychosis, delusions, hallucinations, hostility
The following adverse reactions have also been reported in men:
transient ischemic attacks, convulsions, hypomania, irritability,
dyslipidemias, testicular atrophy, subfertility, and infertility.
The following additional adverse reactions have been reported in
women: hirsutism, virilization, deepening of voice, clitoral
enlargement, breast atrophy, male-pattern baldness, and menstrual
The following adverse reactions have been reported in male and
female adolescents: premature closure of bony epiphyses with
termination of growth, and precocious puberty.
Because these reactions are reported voluntarily from a population
of uncertain size and may include abuse of other agents, it is not
always possible to reliably estimate their frequency or establish a
causal relationship to drug exposure.
Behaviors Associated with Addiction
Continued abuse of testosterone and other anabolic steroids,
addiction is characterized by the following behaviors:
Taking greater dosages than prescribed
Continued drug use despite medical and social problems due to drug
Spending significant time to obtain the drug when supplies of the
drug are interrupted
Giving a higher priority to drug use than other obligations
Having difficulty in discontinuing the drug despite desires and
attempts to do so
Experiencing withdrawal symptoms upon abrupt discontinuation of use
Physical dependence is characterized by withdrawal symptoms after
abrupt drug discontinuation or a significant dose reduction of a
drug. Individuals taking supratherapeutic doses of testosterone may
experience withdrawal symptoms lasting for weeks or months which
include depressed mood, major depression, fatigue, craving,
restlessness, irritability, anorexia, insomnia, decreased libido
and hypogonadotropic hypogonadism.
Drug dependence in individuals using approved doses of testosterone
for approved indications has not been documented.
There have been no reports of acute overdosage with the androgens.
Testosterone Cypionate Dosage and Administration
Prior to initiating Testosterone Cypionate Injection, confirm the
diagnosis of hypogonadism by ensuring that serum testosterone
concentrations have been measured in the morning on at least two
separate days and that these serum testosterone concentrations are
below the normal range.
Testosterone Cypionate Injection is for intramuscular use only.
It should not be given intravenously. Intramuscular injections
should be given deep in the gluteal muscle.
The suggested dosage for Testosterone Cypionate Injection varies
depending on the age, sex, and diagnosis of the individual patient.
Dosage is adjusted according to the patient's response and the
appearance of adverse reactions.
Various dosage regimens have been used to induce pubertal changes
in hypogonadal males; some experts have advocated lower dosages
initially, gradually increasing the dose as puberty progresses,
with or without a decrease to maintenance levels. Other experts
emphasize that higher dosages are needed to induce pubertal changes
and lower dosages can be used for maintenance after puberty. The
chronological and skeletal ages must be taken into consideration,
both in determining the initial dose and in adjusting the dose.
For replacement in the hypogonadal male, 50–400 mg should be
administered every two to four weeks.
Parenteral drug products should be inspected visually for
particulate matter and discoloration prior to administration,
whenever solution and container permit. Warming and shaking the
vial should redissolve any crystals that may have formed during
storage at temperatures lower than recommended.